Virus-like particle (VLP) based vaccination anti-infection prophylaxis has been established in clinical use. Although validated in a proof-of-concept clinical trials in humans, there is no VLP-based vaccine therapy against self-proteins to modulate chronic disease has not been licensed.
This review summarizes the scientific advances recently, identifying interleukin-13 as a very good candidate to validate the concept of anti-cytokine vaccination. Based on numerous clinical studies, the long-term elimination of IL-13 is not expected to trigger the associated target serious side effects and tend to be more secure than the combined target the IL-4 / IL-13. Furthermore, the recent results published on a large scale trial to confirm that deletion of IL-13 is highly effective in atopic dermatitis, a very common condition, and eosinophilic esophagitis.
Clearly different mode of action polyclonal vaccine responses are discussed in detail, suggesting that vaccination anti-IL-13 has the potential exceeds a monoclonal antibody-based approach. Finally, recent data have identified a subset of T helper follicular cells dependent on IL-13 that selectively trigger the accumulation of large IgE in response anaphylactoid allergens. Thus, IL-13 vaccination prophylaxis may have broad applications in a number of allergic conditions.
Virus-Like Particle-Mediated Vaccination against Interleukin –13 May Harbour General Anti-Allergic Potential beyond Atopic Dermatitis. Neuroprotective modulation of microglia effector function following priming with interleukin 4 and 13 :
the current limitations in understanding the mode-of-action them. In recent years the old theory for dual polarization properties of microglia phenotype toward pro or anti-inflammatory has been very challenging. Furthermore, the explanation microglia exposed ontogenesis intrinsic differences between microglia and peripheral myeloid cells, thus further emphasize the need for re-evaluation of the specific behavior of microglia activation, especially in an environment of inflamed central nervous system (CNS).
This review summarizes the recent literature on the critical in vitro and in vivo murine microglia response to immune-modulatory cytokine interleukin 4 (IL4) and interleukin 13 (IL13), ie those driving the so-called anti-inflammatory phenotype . Here we highlight some of the important factors that could influence the outcome of experiments and / or interpretation of in vitro and in vivo studies to evaluate this microglia phenotypical and functional properties of the IL4 / IL13 treatment.
Finally, the relevance of the current therapy of microglia activation IL4 / IL13-induced in both acute and chronic CNS disorders discussed.Osteoarthritis (OA) is a degenerative joint disease that seriously affects the quality of life of patients. Irisin has been reported to regulate bone metabolism through an autocrine mechanism of cellular and play a protective role in OA rats. In this study, the SW1353 chondrosarcoma cell lines were treated with interleukin (IL) -1β and irisin.
This study evaluated the viability of the cells, the level of expression of collagen II (Col II) and matrix metalloproteinase-13 (MMP-13), and the activity of the Wnt / β-catenin and NF-kB signaling pathways in cells treated SW1353. These results suggest that IL-1β can decrease the expression of Col II and increase MMP-13 expression in both mRNA and protein levels, and also activate the Wnt / β-catenin and NF-kB signaling pathway in SW1353 cells.
Interleukin 17B (IL17B) Antibody
abx101512-1ml
Abbexa
1 ml
EUR 712.5
Interleukin 17B (IL17B) Antibody
abx101512-200l
Abbexa
200 µl
EUR 325
Interleukin 17B (IL17B) Antibody
abx101513-100l
Abbexa
100 µl
EUR 275
Interleukin 17B (IL17B) Antibody
20-abx101513
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Interleukin 17B (IL17B) Antibody
abx101513-1ml
Abbexa
1 ml
EUR 775
Interleukin 17B (IL17B) Antibody
abx101513-200l
Abbexa
200 µl
EUR 350
Interleukin 17B (IL17B) Antibody
abx177117-1096tests
Abbexa
10 × 96 tests
EUR 725
Interleukin 17B (IL17B) Antibody
20-abx177117
Abbexa
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Interleukin 17B (IL17B) Antibody
abx177117-596tests
Abbexa
5 × 96 tests
EUR 337.5
Interleukin 17B (IL17B) Antibody
abx177117-96tests
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96 tests
EUR 262.5
Interleukin 17B (IL17B) Antibody
20-abx177118
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Interleukin 17B (IL17B) Antibody
abx330118-100g
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100 µg
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Interleukin 17B (IL17B) Antibody
20-abx330118
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Interleukin 17B (IL17B) Antibody
abx330118-20g
Abbexa
20 µg
EUR 187.5
Interleukin 17B (IL17B) Antibody
abx330118-50g
Abbexa
50 µg
EUR 250
Interleukin 17B (IL17B) Antibody
abx173104-100l
Abbexa
100 µl
EUR 750
Interleukin 17B (IL17B) Antibody
20-abx173104
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Interleukin 17B (IL17B) Antibody
abx173104-1ml
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1 ml
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Interleukin 17B (IL17B) Antibody
abx173104-200l
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200 µl
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Interleukin 17B (IL17B) Antibody
20-abx173105
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Interleukin 17B (IL17B) Antibody
abx173105-1ml
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1 ml
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Interleukin 17B (IL17B) Antibody
20-abx216191
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Interleukin 17B (IL17B) Antibody
abx234226-100ug
Abbexa
100 ug
EUR 661.2
Interleukin 17B (IL17B) Antibody
abx375364-96tests
Abbexa
96 tests
EUR 337.5
Interleukin-17B
AP84010
SAB
1mg
EUR 2640
Interleukin-17B
AP84953
SAB
1mg
EUR 2640
Human Interleukin 17B,IL-17B ELISA Kit
201-12-2166
Shanghai Sunred Biological Technology
96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Human Interleukin 17B,IL-17B ELISA KIT
JOT-EK2165Hu
Jotbody
96 wells
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Human Interleukin 17B (IL-17B) ELISA Kit
MBS3800334-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Human Interleukin 17B (IL-17B) ELISA Kit
MBS3800334-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Human Interleukin 17B (IL-17B) ELISA Kit
MBS3800334-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Human Interleukin 17B (IL-17B) ELISA Kit
MBS3800334-96StripWells
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96-Strip-Wells
EUR 765
Human Interleukin 17B, IL-17B ELISA Kit
MBS164972-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 3460
Human Interleukin 17B, IL-17B ELISA Kit
MBS164972-48StripWells
MyBiosource
48-Strip-Wells
EUR 285
Human Interleukin 17B, IL-17B ELISA Kit
MBS164972-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 1750
Human Interleukin 17B, IL-17B ELISA Kit
MBS164972-96StripWells
MyBiosource
96-Strip-Wells
EUR 425
Human Interleukin 17B, IL-17B ELISA Kit
MBS9304269-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Human Interleukin 17B, IL-17B ELISA Kit
MBS9304269-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Human Interleukin 17B, IL-17B ELISA Kit
MBS9304269-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Human Interleukin 17B, IL-17B ELISA Kit
MBS9304269-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Active Interleukin 17B (IL17B)
APB700Hu01
Cloud-Clone
10ug
EUR 198
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4-APB700Hu01
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Description: Recombinant Human Interleukin 17B expressed in: E.coli
Active Interleukin 17B (IL17B)
MBS2097329-001mg
MyBiosource
0.01mg
EUR 180
Active Interleukin 17B (IL17B)
MBS2097329-005mg
MyBiosource
0.05mg
EUR 330
Active Interleukin 17B (IL17B)
MBS2097329-01mg
MyBiosource
0.1mg
EUR 510
Active Interleukin 17B (IL17B)
MBS2097329-02mg
MyBiosource
0.2mg
EUR 625
Active Interleukin 17B (IL17B)
MBS2097329-05mg
MyBiosource
0.5mg
EUR 1195
Human Interleukin 17B, IL-17B GENLISA ELISA
KBH2165
Krishgen
1 x 96 wells
EUR 286
Recombinant Interleukin 17B (IL17B)
MBS2009066-001mg
MyBiosource
0.01mg
EUR 175
Recombinant Interleukin 17B (IL17B)
MBS2009066-005mg
MyBiosource
0.05mg
EUR 315
Recombinant Interleukin 17B (IL17B)
MBS2009066-01mg
MyBiosource
0.1mg
EUR 475
Recombinant Interleukin 17B (IL17B)
MBS2009066-02mg
MyBiosource
0.2mg
EUR 580
Recombinant Interleukin 17B (IL17B)
MBS2009066-05mg
MyBiosource
0.5mg
EUR 1100
Recombinant Interleukin 17B (IL17B)
MBS2031113-001mg
MyBiosource
0.01mg
EUR 165
Recombinant Interleukin 17B (IL17B)
MBS2031113-005mg
MyBiosource
0.05mg
EUR 285
Recombinant Interleukin 17B (IL17B)
MBS2031113-01mg
MyBiosource
0.1mg
EUR 425
Recombinant Interleukin 17B (IL17B)
MBS2031113-02mg
MyBiosource
0.2mg
EUR 515
Recombinant Interleukin 17B (IL17B)
MBS2031113-05mg
MyBiosource
0.5mg
EUR 980
Interleukin 17B Human Recombinant
rAP-0656
Angio Proteomie
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Recombinant Interleukin 17B (IL17B)
RPB700Hu01
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10ug
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Recombinant Interleukin 17B (IL17B)
4-RPB700Hu01
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5 mg 10ug 50ug 100 ug 200 ug 500 ug 1 mg
Description: Recombinant Human Interleukin 17B expressed in: E.coli
Recombinant Interleukin 17B (IL17B)
RPB700Mu01
Cloud-Clone
10ug
EUR 140
Recombinant Interleukin 17B (IL17B)
RPB700Ra01
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4-RPB700Ra01
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5 mg 10ug 50ug 100 ug 200 ug 500 ug 1 mg
Description: Recombinant Rat Interleukin 17B expressed in: E.coli
IL-17B Interleukin 17B Human Recombinant Protein
PROTQ9UHF5-1
BosterBio
Regular: 25ug
EUR 380.4
Description: Interleukin-17B Human Recombinant produced in E.Coli is a homodimeric, non-disulfide-linked polypeptide chain containing a total of 322 amino acids (2 chains of 161aa) and having a molecular mass of 36.5kDa. The IL-17B is purified by proprietary chromatographic techniques.
Rat Interleukin 17B ELISA Kit
IRTIL17BKT
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EUR 660
Description: Rat Interleukin 17B ELISA Kit
Rat Interleukin 17B ELISA Kit
MBS084786-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Rat Interleukin 17B ELISA Kit
MBS084786-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Rat Interleukin 17B ELISA Kit
MBS084786-5x96StripWells
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5x96-Strip-Wells
EUR 3420
Rat Interleukin 17B ELISA Kit
MBS084786-96StripWells
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Cat Interleukin 17B ELISA Kit
MBS093091-INQUIRE
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Rat Interleukin 17B ELISA Kit
MBS3809320-10x96StripWells
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10x96-Strip-Wells
EUR 6725
Rat Interleukin 17B ELISA Kit
MBS3809320-48StripWells
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48-Strip-Wells
EUR 550
Rat Interleukin 17B ELISA Kit
MBS3809320-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Rat Interleukin 17B ELISA Kit
MBS3809320-96StripWells
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Goat Interleukin 17B ELISA Kit
MBS104797-INQUIRE
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Cavy Interleukin 17B ELISA Kit
MBS085307-INQUIRE
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Fish Interleukin 17B ELISA Kit
MBS058200-INQUIRE
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Camel Interleukin 17B ELISA Kit
MBS101457-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Camel Interleukin 17B ELISA Kit
MBS101457-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Camel Interleukin 17B ELISA Kit
MBS101457-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Camel Interleukin 17B ELISA Kit
MBS101457-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Mouse Interleukin 17B ELISA Kit
MBS098495-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Mouse Interleukin 17B ELISA Kit
MBS098495-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Mouse Interleukin 17B ELISA Kit
MBS098495-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Mouse Interleukin 17B ELISA Kit
MBS098495-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Mouse Interleukin 17B ELISA Kit
IMSIL17BKT
Innovative research
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EUR 624
Description: Mouse Interleukin 17B ELISA Kit
Human Interleukin 17B ELISA Kit
IHUIL17BKT
Innovative research
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EUR 606
Description: Human Interleukin 17B ELISA Kit
Goose Interleukin 17B ELISA Kit
MBS067812-INQUIRE
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Sheep Interleukin 17B ELISA Kit
MBS050683-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Sheep Interleukin 17B ELISA Kit
MBS050683-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Sheep Interleukin 17B ELISA Kit
MBS050683-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Sheep Interleukin 17B ELISA Kit
MBS050683-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Horse Interleukin 17B ELISA Kit
MBS051346-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Horse Interleukin 17B ELISA Kit
MBS051346-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Horse Interleukin 17B ELISA Kit
MBS051346-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Horse Interleukin 17B ELISA Kit
MBS051346-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Human Interleukin 17B ELISA Kit
MBS054459-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Human Interleukin 17B ELISA Kit
MBS054459-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Human Interleukin 17B ELISA Kit
MBS054459-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Human Interleukin 17B ELISA Kit
MBS054459-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Bovine Interleukin 17B ELISA Kit
MBS104131-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Bovine Interleukin 17B ELISA Kit
MBS104131-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Bovine Interleukin 17B ELISA Kit
MBS104131-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Bovine Interleukin 17B ELISA Kit
MBS104131-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Monkey Interleukin 17B ELISA Kit
MBS103412-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Monkey Interleukin 17B ELISA Kit
MBS103412-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Monkey Interleukin 17B ELISA Kit
MBS103412-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Monkey Interleukin 17B ELISA Kit
MBS103412-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Pigeon Interleukin 17B ELISA Kit
MBS084136-INQUIRE
MyBiosource
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Rabbit Interleukin 17B ELISA Kit
MBS084732-INQUIRE
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Canine Interleukin 17B ELISA Kit
MBS055647-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Canine Interleukin 17B ELISA Kit
MBS055647-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Canine Interleukin 17B ELISA Kit
MBS055647-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Canine Interleukin 17B ELISA Kit
MBS055647-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Donkey Interleukin 17B ELISA Kit
MBS062170-INQUIRE
MyBiosource
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Interleukin 17B (IL-17B, Interleukin-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal Interleukin-17-related Factor, IL17B, IL20, NIRF, ZCYTO7, UNQ516/PRO1031) (Biotin)
MBS628368-005mg
MyBiosource
0.05mg
EUR 985
Interleukin 17B (IL-17B, Interleukin-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal Interleukin-17-related Factor, IL17B, IL20, NIRF, ZCYTO7, UNQ516/PRO1031) (Biotin)
MBS628368-5x005mg
MyBiosource
5x0.05mg
EUR 4280
Interleukin 17B (IL-17B, Interleukin-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal Interleukin-17-related Factor, IL17B, IL20, NIRF, ZCYTO7, UNQ516/PRO1031) (APC)
MBS627289-01mg
MyBiosource
0.1mg
EUR 905
Interleukin 17B (IL-17B, Interleukin-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal Interleukin-17-related Factor, IL17B, IL20, NIRF, ZCYTO7, UNQ516/PRO1031) (APC)
MBS627289-5x01mg
MyBiosource
5x0.1mg
EUR 3925
Rat Interleukin 17B (IL17B) Protein
abx067473-100g
Abbexa
100 µg
EUR 587.5
Rat Interleukin 17B (IL17B) Protein
20-abx067473
Abbexa
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10 ug 50 ug 100 ug 200 ug 1 mg
Rat Interleukin 17B (IL17B) Protein
abx067473-10g
Abbexa
10 µg
EUR 225
Rat Interleukin 17B (IL17B) Protein
abx067473-50g
Abbexa
50 µg
EUR 412.5
Hamster Interleukin 17B ELISA Kit
MBS066994-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Hamster Interleukin 17B ELISA Kit
MBS066994-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Hamster Interleukin 17B ELISA Kit
MBS066994-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Hamster Interleukin 17B ELISA Kit
MBS066994-96StripWells
MyBiosource
96-Strip-Wells
EUR 765
Porcine Interleukin 17B ELISA Kit
MBS060330-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
Porcine Interleukin 17B ELISA Kit
MBS060330-48StripWells
MyBiosource
48-Strip-Wells
EUR 550
Porcine Interleukin 17B ELISA Kit
MBS060330-5x96StripWells
MyBiosource
5x96-Strip-Wells
EUR 3420
Porcine Interleukin 17B ELISA Kit
MBS060330-96StripWells
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96-Strip-Wells
EUR 765
Chicken Interleukin 17B ELISA Kit
MBS075307-INQUIRE
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Human Interleukin 17B (IL17B) Protein
abx067475-100g
Abbexa
100 µg
EUR 375
Instead, irisin identified to reverse the effects of IL-1β to IL-1β-induced SW1353 cells. These results indicate that treatment irisin may have a cartilage-protective role model SW1353 cell-induced IL-1β.
