Efficacy and Safety of Lebrikizumab, a High-Affinity Interleukin 13 Inhibitor, in Adults With Moderate to Severe Atopic Dermatitis: A Phase 2b Randomized Clinical Trial.
Interleukin 13 (IL-13) is a central pathogenic mediator of driving some of the features of atopic dermatitis (AD) evaluated the efficacy and safety pathophysiology.To lebrikizumab, novel, high-affinity, monoclonal antibody targeting the IL-13 which selectively prevents the formation of IL-13Rα1 / IL- 4Rα heterodimer receptor complex signals, in adults with moderate to severe AD.A phase 2b, double-blind, placebo-controlled, dose-ranging clinical trial randomized lebrikizumab injections every 4 weeks or every 2 weeks was conducted from January 23, 2018, May 23, 2019 at 57 US centers. Participants adults 18 years or older with moderate to severe AD.Patients were randomized 2: 3: 3: 3 with placebo every 2 weeks or subcutaneous injections lebrikizumab at the following doses: 125 mg every 4 weeks (250 mg loading dose [LD]), 250 mg every 4 weeks (500-mg LD), or 250 mg every 2 weeks (LD 500-mg at baseline and weeks 2) .
the primary end point was the percentage change in Eczema Area and Severity Index (EASI) (baseline to week 16 ). Secondary end points for week 16 included the proportion of patients who achieve Investigator Global Assessment score of 0 or 1 (IGA 0/1); EASI increase of at least 50%, 75%, or 90% of the baseline; the percentage change in the numerical rating scale pruritus (NRS) score goals; and NRS pruritus scored an increase of at least 4 points. safety assessment including overall treatment-emergent adverse events.A of 280 patients (mean [SD] age, 39.3 [17.5] years; 166 [59.3%] women) were randomly assigned placebo (n = 52) or lebrikizumab at a dose of 125 mg every 4 weeks (n = 73), 250 mg every 4 weeks (n = 80), or 250 mg every 2 weeks (n = 75).
Compared with placebo (EASI squares mean [SD] percentage change, -41.1% [56.5%]), lebrikizumab group showed a statistically significant increase in the dose-dependent primary endpoint at Week 16 vs. placebo: 125 mg every 4 weeks (-62.3% [37.3%], P = 0.02), 250 mg every 4 weeks (-69.2% [38.3%], P = 0.002), and 250 mg every 2 week (-72.1% [37.2%], P <0.001). Difference vs placebo-treated patients (2 of 44 [4.5%]) in pruritus NRS increase of at least 4 points seen as the beginning day two on lebrikizumab high dose group (9 of 59 [15.3%]).
Treatment-emergent adverse events were reported in 24 of 52 patients with placebo (46.2%) and in patients lebrikizumab as follows: 42 of 73 (57.5%) to 125 mg every 4 weeks, 39 of 80 (48.8% ) to 250 mg every 4 weeks, and 46 of 75 (61.3%) to 250 mg every 2 weeks; mostly mild to moderate and did not lead to discontinuation.
low rate of injection-site reactions (1 of 52 [1.9%] in the placebo group vs. 13 of 228 [5.7%] in all groups lebrikizumab), herpes virus infection (2 [3.8%] vs 8 [3 , 5%]), and conjunctivitis (0% vs 6 [2.6%]) were reported.During 16 weeks of treatment, the efficacy lebrikizumab supplied quickly, depending on the dose in a variety of clinical manifestations in adult patients with moderate to severe and demonstrated safety profile profitable. This data supports the central role of IL-13 in the pathophysiology of AD. If these findings are replicated in phase 3 studies
Signaling through interleukin -4 and interleukin – 13 cholangiocyte TMEM16A receptor complexes regulate the expression and secretion of bile.
While TMEM16A cholangiocyte activity is regulated by extracellular ATP binding membrane purinergic receptors, channels of expression is regulated by interleukin-4 (IL-4) through an unknown mechanism. The purpose of this study is therefore to identify the signaling pathways involved in the expression and secretion TMEM16A cholangiocyte.
Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx103023 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx103024 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx103025 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx104858 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx129961 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx130197 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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20-abx130814 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx149072-100ug | Abbexa | 100 ug | EUR 510 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx140056-01mg | Abbexa | 0.1 mg | EUR 376.8 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx140058-01mg | Abbexa | 0.1 mg | EUR 360 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx015891-100ug | Abbexa | 100 ug | EUR 493.2 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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20-abx002170 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx270003 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx270019 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx270026 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx270033 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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20-abx213623 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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20-abx214719 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx173126 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody |
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20-abx173127 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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20-abx338834 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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20-abx324195 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx430203-200ul | Abbexa | 200 ul | EUR 343.2 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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20-abx323727 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx002170-100l | Abbexa | 100 µl | EUR 400 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx002170-20l | Abbexa | 20 µl | EUR 175 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx002170-50l | Abbexa | 50 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx104858-100g | Abbexa | 100 µg | EUR 850 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx104858-20g | Abbexa | 20 µg | EUR 287.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx104858-50g | Abbexa | 50 µg | EUR 375 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103023-100l | Abbexa | 100 µl | EUR 262.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103023-1ml | Abbexa | 1 ml | EUR 712.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103023-200l | Abbexa | 200 µl | EUR 325 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103024-100l | Abbexa | 100 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103024-1ml | Abbexa | 1 ml | EUR 775 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103024-200l | Abbexa | 200 µl | EUR 350 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103025-100l | Abbexa | 100 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103025-1ml | Abbexa | 1 ml | EUR 775 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx103025-200l | Abbexa | 200 µl | EUR 350 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx159563-100g | Abbexa | 100 µg | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx159563-10g | Abbexa | 10 µg | EUR 187.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx159563-50g | Abbexa | 50 µg | EUR 250 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx129961-100l | Abbexa | 100 µl | EUR 287.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx129961-1ml | Abbexa | 1 ml | EUR 850 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx129961-200l | Abbexa | 200 µl | EUR 375 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx130197-100l | Abbexa | 100 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx130197-1ml | Abbexa | 1 ml | EUR 775 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx130197-200l | Abbexa | 200 µl | EUR 350 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx173126-100l | Abbexa | 100 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx173126-1ml | Abbexa | 1 ml | EUR 750 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx173126-200l | Abbexa | 200 µl | EUR 337.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx173127-100l | Abbexa | 100 µl | EUR 900 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx173127-1ml | Abbexa | 1 ml | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx173127-200l | Abbexa | 200 µl | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx213623-100l | Abbexa | 100 µl | EUR 250 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx025269-400l | Abbexa | 400 µl | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx025269-80l | Abbexa | 80 µl | EUR 518.75 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx015891-1mg | Abbexa | 1 mg | EUR 362.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx270003-1ml | Abbexa | 1 ml | EUR 387.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx270003-200l | Abbexa | 200 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx270019-1ml | Abbexa | 1 ml | EUR 387.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx270019-200l | Abbexa | 200 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx270026-1ml | Abbexa | 1 ml | EUR 387.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx270026-200l | Abbexa | 200 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx270033-1ml | Abbexa | 1 ml | EUR 387.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx270033-200l | Abbexa | 200 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx130814-100l | Abbexa | 100 µl | EUR 262.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx130814-500l | Abbexa | 500 µl | EUR 337.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx149072-1096tests | Abbexa | 10 × 96 tests | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx149072-596tests | Abbexa | 5 × 96 tests | EUR 387.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx149072-96tests | Abbexa | 96 tests | EUR 300 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx139566-100l | Abbexa | 100 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx139566-500l | Abbexa | 500 µl | EUR 1837.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx139567-100l | Abbexa | 100 µl | EUR 275 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx139567-500l | Abbexa | 500 µl | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx214719-100g | Abbexa | 100 µg | EUR 350 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx214719-25g | Abbexa | 25 µg | EUR 250 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx228886-100g | Abbexa | 100 µg | EUR 100 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx228887-100g | Abbexa | 100 µg | EUR 50 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx239909-100l | Abbexa | 100 µl | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx239909-50l | Abbexa | 50 µl | EUR 350 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx338834-100l | Abbexa | 100 µl | EUR 250 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx338834-50l | Abbexa | 50 µl | EUR 162.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx323727-100g | Abbexa | 100 µg | EUR 250 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx323727-50g | Abbexa | 50 µg | EUR 187.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx324195-100g | Abbexa | 100 µg | EUR 250 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx324195-50g | Abbexa | 50 µg | EUR 187.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx375003-96tests | Abbexa | 96 tests | EUR 225 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx412774-200l | Abbexa | 200 µl | EUR 362.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx412877-200l | Abbexa | 200 µl | EUR 462.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx412878-200l | Abbexa | 200 µl | EUR 337.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx413298-200l | Abbexa | 200 µl | EUR 425 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx413741-200l | Abbexa | 200 µl | EUR 462.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx413847-200l | Abbexa | 200 µl | EUR 362.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx414178-200l | Abbexa | 200 µl | EUR 362.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx414537-200l | Abbexa | 200 µl | EUR 350 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx414539-200l | Abbexa | 200 µl | EUR 487.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx415231-200l | Abbexa | 200 µl | EUR 362.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx415240-200l | Abbexa | 200 µl | EUR 362.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody |
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abx430203-200l | Abbexa | 200 µl | EUR 250 |
Rabbit Anti-Human Interleukin 6 receptor (IL-6RCD126, gp80/IL-6RA) |
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AB-22124 | Alpha Diagnostics | 50 ul | EUR 562.8 |
Interleukin-2 receptor subunit alpha |
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AP84148 | SAB | 1mg | EUR 2640 |
Interleukin-2 receptor subunit alpha |
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AP84395 | SAB | 1mg | EUR 2640 |
Interleukin-2 receptor subunit alpha |
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AP84505 | SAB | 1mg | EUR 2640 |
Interleukin-2 receptor subunit alpha |
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AP84541 | SAB | 1mg | EUR 2640 |
Interleukin-2 receptor subunit alpha |
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AP84626 | SAB | 1mg | EUR 2640 |
Interleukin-2 receptor subunit alpha |
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AP85055 | SAB | 1mg | EUR 2640 |
Rabbit Anti-Human Interleukin-1 receptor-like 1 (IL1RL1) IgG (aff pure) |
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AB-23064-A | Alpha Diagnostics | 100ug | EUR 578.4 |
Rabbit Anti-Human Interleukin-1 receptor-like 1 (IL1RL1) IgG (aff pure) |
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AB-23065-A | Alpha Diagnostics | 100ug | EUR 578.4 |
Rabbit Anti-Human Interleukin-1 receptor-like 1 (IL1RL1) IgG (aff pure) |
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AB-23066-A | Alpha Diagnostics | 100ug | EUR 578.4 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx140057-01mg | Abbexa | 0.1 mg | EUR 410.4 |
Interleukin 2 Receptor Alpha (IL2Ra) Antibody (PE) |
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20-abx270765 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody (PE) |
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20-abx270781 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody (PE) |
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20-abx270788 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody (PE) |
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20-abx270795 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx270765-1ml | Abbexa | 1 ml | EUR 625 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx270765-200l | Abbexa | 200 µl | EUR 525 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx270781-1ml | Abbexa | 1 ml | EUR 1025 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx270781-200l | Abbexa | 200 µl | EUR 625 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx270788-1ml | Abbexa | 1 ml | EUR 1025 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx270788-200l | Abbexa | 200 µl | EUR 625 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx270795-1ml | Abbexa | 1 ml | EUR 625 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx270795-200l | Abbexa | 200 µl | EUR 525 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx139568-100l | Abbexa | 100 µl | EUR 400 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx139568-500l | Abbexa | 500 µl | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx228890-100g | Abbexa | 100 µg | EUR 125 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx229426-100g | Abbexa | 100 µg | EUR 62.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx412879-200l | Abbexa | 200 µl | EUR 862.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx413745-200l | Abbexa | 200 µl | EUR 487.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx414179-200l | Abbexa | 200 µl | EUR 637.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx414538-200l | Abbexa | 200 µl | EUR 512.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (PE) |
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abx415232-200l | Abbexa | 200 µl | EUR 637.5 |
Active Interleukin 2 Receptor Alpha (IL2Ra) |
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APB837Hu61 | Cloud-Clone | 10ug | EUR 204 |
Active Interleukin 2 Receptor Alpha (IL2Ra) |
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APB837Mu02 | Cloud-Clone | 10ug | EUR 192 |
Active Interleukin 2 Receptor Alpha (IL2Ra) |
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4-APB837Mu02 | Cloud-Clone |
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Description: Recombinant Mouse Interleukin 2 Receptor Alpha expressed in: E.coli |
Active Interleukin 2 Receptor Alpha (IL2Ra) |
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RPU54941-100ug | Biomatik Corporation | 100ug | EUR 591.8 |
Active Interleukin 2 Receptor Alpha (IL2Ra) |
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RPU54941-1mg | Biomatik Corporation | 1mg | EUR 2620.8 |
Active Interleukin 2 Receptor Alpha (IL2Ra) |
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RPU54941-50ug | Biomatik Corporation | 50ug | EUR 475.2 |
Interleukin 2 Receptor Alpha (IL2Ra) Antibody (APC) |
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20-abx270533 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody (APC) |
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20-abx270549 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody (APC) |
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20-abx270556 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2Ra) Antibody (APC) |
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20-abx270563 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody (HRP) |
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20-abx336174 | Abbexa |
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Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx270533-1ml | Abbexa | 1 ml | EUR 737.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx270533-200l | Abbexa | 200 µl | EUR 612.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx270549-1ml | Abbexa | 1 ml | EUR 1200 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx270549-200l | Abbexa | 200 µl | EUR 737.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx270556-1ml | Abbexa | 1 ml | EUR 1200 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx270556-200l | Abbexa | 200 µl | EUR 737.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx270563-1ml | Abbexa | 1 ml | EUR 737.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx270563-200l | Abbexa | 200 µl | EUR 612.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx139571-100l | Abbexa | 100 µl | EUR 400 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx139571-500l | Abbexa | 500 µl | Ask for price |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx228891-100g | Abbexa | 100 µg | EUR 125 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (APC) |
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abx229427-100g | Abbexa | 100 µg | EUR 62.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (HRP) |
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abx336174-100g | Abbexa | 100 µg | EUR 362.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (HRP) |
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abx336174-20g | Abbexa | 20 µg | EUR 162.5 |
Interleukin 2 Receptor Alpha (IL2RA) Antibody (HRP) |
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abx336174-50g | Abbexa | 50 µg | EUR 250 |
The study was conducted in normal mice cholangiocyte polarized monolayers, Mz-Cha-1 human bladder cells, and cholangiocytes isolated from murine liver tissue. The results showed that all models of bile reveal a complex receptor IL-4RA / IL-13Ra1.